/* Design Dashboard Sidebar */
:root {
    --primary-color: #2563eb;
    --secondary-color: #64748b;
    --accent-color: #3b82f6;
    --success-color: #10b981;
    --info-color: #06b6d4;
    --warning-color: #f59e0b;
    --danger-color: #ef4444;
    --sidebar-bg: #1e293b;
    --sidebar-hover: #334155;
    --main-bg: #f8fafc;
    --surface: #ffffff;
    --border-color: #e2e8f0;
    --text-dark: #0f172a;
    --text-light: #64748b;
    --text-white: #ffffff;
}

/* Layout Grid */
.layout-grid {
    display: grid;
    grid-template-columns: 280px 1fr;
    height: 100vh;
    margin: 0;
    font-family: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;
}

/* Sidebar */
.sidebar {
    background: var(--sidebar-bg);
    color: var(--text-white);
    display: flex;
    flex-direction: column;
    border-right: 1px solid var(--border-color);
}

.sidebar-header {
    padding: 2rem 1.5rem;
    border-bottom: 1px solid var(--sidebar-hover);
}

.logo {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    font-size: 1.5rem;
    font-weight: 700;
    margin-bottom: 0.5rem;
}

.logo i {
    color: var(--primary-color);
}

.institution {
    font-size: 0.875rem;
    color: var(--text-light);
}

.sidebar-nav {
    flex: 1;
    padding: 1.5rem 0;
}

.nav-item {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    padding: 0.875rem 1.5rem;
    color: var(--text-white);
    text-decoration: none;
    transition: all 0.2s ease;
    border-left: 3px solid transparent;
}

.nav-item:hover {
    background: var(--sidebar-hover);
    color: var(--text-white);
}

.nav-item.active {
    background: var(--sidebar-hover);
    border-left-color: var(--primary-color);
    color: var(--text-white);
}

.nav-item.disabled {
    opacity: 0.5;
    pointer-events: none;
}

.sidebar-footer {
    padding: 1.5rem;
    border-top: 1px solid var(--sidebar-hover);
}

.credits {
    font-size: 0.75rem;
    color: var(--text-light);
}

.credit-item {
    margin-bottom: 0.25rem;
}

/* Main Content */
.main-content {
    background: var(--main-bg);
    overflow-y: auto;
    padding: 2rem;
}

.content-header {
    margin-bottom: 3rem;
}

.content-header h1 {
    font-size: 2.25rem;
    font-weight: 700;
    color: var(--text-dark);
    margin-bottom: 0.5rem;
}

.content-header p {
    font-size: 1.125rem;
    color: var(--text-light);
}

/* Applications Grid */
.applications-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(400px, 1fr));
    gap: 2rem;
    margin-bottom: 3rem;
}

.app-tile {
    background: var(--surface);
    border-radius: 16px;
    padding: 2rem;
    border: 1px solid var(--border-color);
    cursor: pointer;
    transition: all 0.3s ease;
    display: flex;
    flex-direction: column;
}

.app-tile:hover {
    transform: translateY(-4px);
    box-shadow: 0 20px 48px rgba(0,0,0,0.1);
    border-color: var(--primary-color);
}

.app-tile-icon {
    display: flex;
    align-items: center;
    justify-content: center;
    width: 80px;
    height: 80px;
    border-radius: 20px;
    margin-bottom: 1.5rem;
    font-size: 2rem;
}

.app-tile-primary .app-tile-icon {
    background: linear-gradient(135deg, var(--primary-color), var(--accent-color));
    color: white;
}

.app-tile-secondary .app-tile-icon {
    background: linear-gradient(135deg, var(--secondary-color), #94a3b8);
    color: white;
}

.app-tile-content {
    flex: 1;
    margin-bottom: 1.5rem;
}

.app-tile-content h3 {
    font-size: 1.5rem;
    font-weight: 600;
    color: var(--text-dark);
    margin-bottom: 0.75rem;
}

.app-tile-content p {
    color: var(--text-light);
    margin-bottom: 1rem;
}

.app-tile-features {
    display: flex;
    flex-direction: column;
    gap: 0.25rem;
}

.feature {
    font-size: 0.875rem;
    color: var(--text-light);
}

.app-tile-action {
    display: flex;
    align-items: center;
    justify-content: space-between;
    padding: 1rem;
    background: var(--main-bg);
    border-radius: 12px;
    font-weight: 600;
}

.app-tile-primary .app-tile-action {
    color: var(--primary-color);
}

.app-tile-secondary .app-tile-action {
    color: var(--secondary-color);
}

/* Quick Info */
.quick-info {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 1.5rem;
}

.info-card {
    background: var(--surface);
    padding: 1.5rem;
    border-radius: 12px;
    border: 1px solid var(--border-color);
    display: flex;
    align-items: flex-start;
    gap: 1rem;
}

.info-card i {
    width: 48px;
    height: 48px;
    display: flex;
    align-items: center;
    justify-content: center;
    background: var(--main-bg);
    border-radius: 12px;
    color: var(--primary-color);
    font-size: 1.25rem;
    flex-shrink: 0;
}

.info-card h4 {
    font-size: 1rem;
    font-weight: 600;
    color: var(--text-dark);
    margin-bottom: 0.25rem;
}

.info-card p {
    font-size: 0.875rem;
    color: var(--text-light);
    margin: 0;
}

/* Form Styling */
.form-container {
    max-width: 1200px;
    margin: 0 auto;
}

.form-section {
    background: var(--surface);
    border-radius: 16px;
    padding: 2rem;
    margin-bottom: 2rem;
    border: 1px solid var(--border-color);
}

.section-header {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    margin-bottom: 1.5rem;
    padding-bottom: 1rem;
    border-bottom: 1px solid var(--border-color);
    justify-content: space-between;
}

.section-header i {
    color: var(--primary-color);
    font-size: 1.25rem;
}

.section-header h3 {
    margin: 0;
    color: var(--text-dark);
    font-weight: 600;
    flex: 1;
}

.section-header .btn {
    margin-left: auto;
}

.form-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 1.5rem;
}

.form-group {
    display: flex;
    flex-direction: column;
}

.form-label {
    display: flex;
    align-items: center;
    gap: 0.5rem;
    font-weight: 500;
    color: var(--text-dark);
    margin-bottom: 0.5rem;
}

.form-label i {
    color: var(--primary-color);
    width: 16px;
}

.form-control, .form-select {
    border: 1px solid var(--border-color);
    border-radius: 8px;
    padding: 0.75rem;
    transition: all 0.2s ease;
}

.form-control:focus, .form-select:focus {
    border-color: var(--primary-color);
    box-shadow: 0 0 0 0.2rem rgba(37, 99, 235, 0.25);
    outline: none;
}

/* Samples Container */
.samples-container {
    background: var(--main-bg);
    border-radius: 12px;
    padding: 1.5rem;
    border: 1px solid var(--border-color);
}

.samples-header {
    display: grid;
    grid-template-columns: 1fr 1fr auto;
    gap: 1rem;
    padding: 0.75rem;
    background: var(--surface);
    border-radius: 8px;
    margin-bottom: 1rem;
    font-weight: 600;
    color: var(--text-dark);
}



.sample-row {
    display: grid;
    grid-template-columns: 1fr 1fr auto;
    gap: 1rem;
    padding: 0.75rem;
    border-radius: 8px;
    margin-bottom: 0.5rem;
    transition: all 0.2s ease;
}

.sample-row:hover {
    background: var(--surface);
}

.sample-row .form-control {
    border-radius: 6px;
    padding: 0.5rem;
}

.btn-remove {
    background: var(--danger-color);
    border: none;
    color: white;
    border-radius: 6px;
    padding: 0.5rem 0.75rem;
    transition: all 0.2s ease;
}

.btn-remove:hover {
    background: #dc2626;
    transform: scale(1.05);
}

/* Submit Container */
.submit-container {
    display: flex;
    gap: 1rem;
    justify-content: center;
    align-items: center;
}

.btn-primary {
    background: linear-gradient(135deg, var(--primary-color), var(--accent-color));
    border: none;
    color: white;
    padding: 0.875rem 2rem;
    border-radius: 12px;
    font-weight: 600;
    transition: all 0.3s ease;
    box-shadow: 0 4px 14px rgba(37, 99, 235, 0.3);
}

.btn-primary:hover {
    transform: translateY(-2px);
    box-shadow: 0 8px 25px rgba(37, 99, 235, 0.4);
}

.btn-outline-secondary {
    border: 2px solid var(--secondary-color);
    color: var(--secondary-color);
    background: transparent;
    padding: 0.875rem 2rem;
    border-radius: 12px;
    font-weight: 600;
    transition: all 0.3s ease;
}

.btn-outline-secondary:hover {
    background: var(--secondary-color);
    color: white;
    transform: translateY(-2px);
}

.btn-outline-primary {
    border: 2px solid var(--primary-color);
    color: var(--primary-color);
    background: transparent;
    border-radius: 8px;
    font-weight: 500;
    transition: all 0.2s ease;
}

.btn-outline-primary:hover {
    background: var(--primary-color);
    color: white;
}

/* Coming Soon Page */
.coming-soon-container {
    display: flex;
    justify-content: center;
    align-items: center;
    min-height: 60vh;
}

.coming-soon-card {
    background: var(--surface);
    border-radius: 20px;
    padding: 3rem;
    text-align: center;
    border: 1px solid var(--border-color);
    max-width: 600px;
    box-shadow: 0 8px 32px rgba(0,0,0,0.1);
}

.coming-soon-icon {
    width: 120px;
    height: 120px;
    border-radius: 50%;
    background: linear-gradient(135deg, var(--secondary-color), #94a3b8);
    display: flex;
    align-items: center;
    justify-content: center;
    margin: 0 auto 2rem;
    font-size: 3rem;
    color: white;
}

.coming-soon-content h2 {
    font-size: 2rem;
    font-weight: 700;
    color: var(--text-dark);
    margin-bottom: 1rem;
}

.coming-soon-content p {
    font-size: 1.125rem;
    color: var(--text-light);
    margin-bottom: 2rem;
}

.feature-list {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 1rem;
    margin-bottom: 2rem;
}

.feature-item {
    display: flex;
    align-items: center;
    gap: 0.75rem;
    padding: 1rem;
    background: var(--main-bg);
    border-radius: 12px;
    border: 1px solid var(--border-color);
}

.feature-item i {
    color: var(--primary-color);
    font-size: 1.25rem;
    width: 24px;
    text-align: center;
}

.feature-item span {
    font-weight: 500;
    color: var(--text-dark);
}

.coming-soon-action {
    margin-top: 2rem;
}

/* Success Page Styles */
.success-container {
    display: flex;
    justify-content: center;
    align-items: center;
    min-height: 60vh;
}

.success-card {
    background: var(--surface);
    border-radius: 20px;
    padding: 3rem;
    text-align: center;
    border: 1px solid var(--border-color);
    max-width: 700px;
    box-shadow: 0 8px 32px rgba(0,0,0,0.1);
}

.success-icon {
    width: 120px;
    height: 120px;
    border-radius: 50%;
    background: linear-gradient(135deg, #059669, #10b981);
    display: flex;
    align-items: center;
    justify-content: center;
    margin: 0 auto 2rem;
    font-size: 3rem;
    color: white;
}

.success-content h2 {
    font-size: 2rem;
    font-weight: 700;
    color: var(--text-dark);
    margin-bottom: 1rem;
}

.success-content p {
    font-size: 1.125rem;
    color: var(--text-light);
    margin-bottom: 2rem;
}

.patient-summary {
    background: var(--main-bg);
    border-radius: 12px;
    padding: 2rem;
    margin: 2rem 0;
    border: 1px solid var(--border-color);
}

.patient-summary h4 {
    color: var(--text-dark);
    margin-bottom: 1.5rem;
    font-weight: 600;
}

.summary-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 1rem;
}

.summary-item {
    padding: 0.75rem;
    background: var(--surface);
    border-radius: 8px;
    border: 1px solid var(--border-color);
    font-size: 0.95rem;
}

.summary-item strong {
    color: var(--primary-color);
}

.success-actions {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: 1rem;
    margin-top: 2rem;
}

.success-actions .btn {
    padding: 0.875rem 1.5rem;
    font-weight: 600;
    border-radius: 12px;
    transition: all 0.3s ease;
}

.success-actions .btn:hover {
    transform: translateY(-2px);
    box-shadow: 0 8px 25px rgba(0,0,0,0.15);
}

/* Responsive */
@media (max-width: 768px) {
    .layout-grid {
        grid-template-columns: 1fr;
        grid-template-rows: auto 1fr;
    }
    
    .sidebar {
        order: 2;
        flex-direction: row;
        height: auto;
    }
    
    .sidebar-header {
        flex: 1;
    }
    
    .sidebar-nav {
        display: flex;
        gap: 1rem;
        padding: 1rem;
    }
    
    .sidebar-footer {
        display: none;
    }
    
    .form-grid {
        grid-template-columns: 1fr;
    }
    
    .samples-header, .sample-row {
        grid-template-columns: 1fr 1fr auto;
    }
    
    .submit-container {
        flex-direction: column;
    }
    
    .feature-list {
        grid-template-columns: 1fr;
    }
}

/* Navigation */
.navbar-brand {
    font-weight: 600;
    font-size: 1.4rem;
    letter-spacing: -0.02em;
}

.navbar-primary {
    background: linear-gradient(90deg, var(--primary-color) 0%, var(--secondary-color) 100%) !important;
    backdrop-filter: blur(10px);
    border-bottom: 1px solid rgba(255,255,255,0.1);
    box-shadow: 0 2px 20px rgba(0,0,0,0.08);
}

/* Hero Section */
.hero-section {
    background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
    color: white;
    padding: 3rem 2rem;
    border-radius: 15px;
    margin-bottom: 2rem;
    box-shadow: 0 10px 30px rgba(0,0,0,0.1);
}

.hero-section h1 {
    margin-bottom: 1rem;
    text-shadow: 2px 2px 4px rgba(0,0,0,0.3);
}

.hero-section .lead {
    color: rgba(255,255,255,0.9);
    font-size: 1.2rem;
}

/* Cartes modernes avec glassmorphisme */
.card {
    border-radius: 16px;
    border: 1px solid rgba(255,255,255,0.3);
    background: rgba(255,255,255,0.9);
    backdrop-filter: blur(10px);
    box-shadow: 0 8px 32px rgba(0,0,0,0.06);
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
}

.card:hover {
    transform: translateY(-4px);
    box-shadow: 0 20px 48px rgba(0,0,0,0.12);
    border-color: rgba(255,255,255,0.5);
}

.card-header {
    border-bottom: 1px solid rgba(0,0,0,0.08);
    padding: 1.5rem;
    background: linear-gradient(135deg, rgba(255,255,255,0.8) 0%, rgba(255,255,255,0.4) 100%);
    border-radius: 16px 16px 0 0;
}

.card-body {
    padding: 2rem;
}

/* Form Styling */
.form-label {
    color: var(--primary-color);
    margin-bottom: 0.5rem;
}

.form-control, .form-select {
    border-radius: 8px;
    border: 2px solid #e9ecef;
    padding: 0.75rem;
    transition: border-color 0.3s ease, box-shadow 0.3s ease;
}

.form-control:focus, .form-select:focus {
    border-color: var(--primary-color);
    box-shadow: 0 0 0 0.2rem rgba(139, 115, 85, 0.25);
    background: rgba(255,255,255,0.9);
}

.form-text {
    color: var(--dark-gray);
    font-size: 0.875rem;
}

/* Section Headers */
.section-header h5 {
    font-weight: 600;
    margin-bottom: 1rem;
}

/* Buttons */
.btn {
    border-radius: 8px;
    padding: 0.75rem 1.5rem;
    font-weight: 600;
    transition: all 0.3s ease;
    border: none;
}

.btn-primary {
    background: linear-gradient(135deg, var(--primary-color) 0%, var(--accent-color) 100%);
    border: none;
    border-radius: 12px;
    font-weight: 500;
    letter-spacing: 0.01em;
    box-shadow: 0 4px 14px rgba(139, 115, 85, 0.3);
    transition: all 0.3s cubic-bezier(0.4, 0, 0.2, 1);
}

.btn-primary:hover {
    transform: translateY(-2px);
    box-shadow: 0 8px 25px rgba(139, 115, 85, 0.4);
    background: linear-gradient(135deg, var(--accent-color) 0%, var(--primary-color) 100%);
}

.btn-lg {
    padding: 0.875rem 1.5rem;
    font-size: 1rem;
    font-weight: 500;
}

/* Alerts */
.alert {
    border-radius: 10px;
    border: none;
    box-shadow: 0 4px 15px rgba(0,0,0,0.1);
}

.alert-danger {
    background: linear-gradient(135deg, #f8d7da 0%, #f5c6cb 100%);
    color: #721c24;
}

/* Info Cards */
.card.border-info {
    border: 2px solid var(--info-color) !important;
}

.bg-info {
    background: linear-gradient(135deg, var(--info-color) 0%, #0e7490 100%) !important;
}

/* Icons */
.fas, .far {
    margin-right: 0.5rem;
}

/* Footer */
footer {
    margin-top: auto;
    border-top: 1px solid #e9ecef;
}

/* Responsive Design */
@media (max-width: 768px) {
    .hero-section {
        padding: 2rem 1rem;
    }
    
    .hero-section h1 {
        font-size: 2rem;
    }
    
    .card-body {
        padding: 1.5rem;
    }
}

/* Loading States */
.btn:disabled {
    opacity: 0.6;
    cursor: not-allowed;
}

/* Success States */
.text-success {
    color: var(--success-color) !important;
}

.bg-success {
    background: linear-gradient(135deg, var(--success-color) 0%, #047857 100%) !important;
}

/* Custom Scrollbar */
::-webkit-scrollbar {
    width: 8px;
}

::-webkit-scrollbar-track {
    background: #f1f1f1;
    border-radius: 10px;
}

::-webkit-scrollbar-thumb {
    background: var(--primary-color);
    border-radius: 10px;
}

::-webkit-scrollbar-thumb:hover {
    background: #3f5a36;
}

/* Animation for form validation */
.was-validated .form-control:valid {
    border-color: var(--success-color);
}

.was-validated .form-control:invalid {
    border-color: var(--danger-color);
}

/* Conteneurs échantillons modernes */
.samples-container {
    background: rgba(255,255,255,0.8);
    backdrop-filter: blur(10px);
    border-radius: 16px;
    padding: 1.5rem;
    border: 1px solid rgba(255,255,255,0.3);
    box-shadow: 0 4px 16px rgba(0,0,0,0.04);
}

.samples-table {
    background: linear-gradient(135deg, var(--light-gray) 0%, rgba(255,255,255,0.9) 100%);
    border-radius: 12px;
    padding: 1.25rem;
    border: 1px solid rgba(0,0,0,0.05);
}

.sample-row {
    margin-bottom: 0.5rem;
    transition: all 0.3s ease;
}

.sample-row:hover {
    background: linear-gradient(135deg, rgba(255,255,255,0.8) 0%, var(--light-gray) 100%);
    border-radius: 8px;
    padding: 0.5rem;
    margin-left: -0.5rem;
    margin-right: -0.5rem;
    box-shadow: 0 2px 8px rgba(0,0,0,0.06);
}

.sample-row .form-control-sm {
    font-size: 0.9rem;
    padding: 0.5rem 0.75rem;
}

.btn-outline-primary:hover,
.btn-outline-danger:hover {
    transform: translateY(-1px);
    box-shadow: 0 2px 8px rgba(0,0,0,0.15);
}

/* Cartes d'applications modernes */
.app-card {
    transition: all 0.4s cubic-bezier(0.4, 0, 0.2, 1);
    border-radius: 20px;
    border: 1px solid rgba(255,255,255,0.3);
    background: rgba(255,255,255,0.85);
    backdrop-filter: blur(15px);
}

.app-card:hover {
    transform: translateY(-8px) rotate(0.5deg);
    box-shadow: 0 25px 50px rgba(0,0,0,0.15);
    border-color: rgba(255,255,255,0.6);
}

.app-icon {
    padding: 1.25rem;
    background: linear-gradient(135deg, var(--light-gray) 0%, rgba(255,255,255,0.8) 100%);
    border-radius: 16px;
    display: inline-block;
    margin: 0 auto;
    border: 1px solid rgba(0,0,0,0.05);
    box-shadow: 0 4px 12px rgba(0,0,0,0.08);
}

.app-card .btn {
    font-weight: 500;
    padding: 0.875rem 1.75rem;
    border-radius: 12px;
    box-shadow: 0 4px 12px rgba(139, 115, 85, 0.25);
}

/* Sections hero modernes */
.hero-section-home {
    background: linear-gradient(135deg, var(--primary-color) 0%, var(--secondary-color) 100%);
    color: white;
    padding: 3rem 2rem;
    border-radius: 16px;
    margin-bottom: 2.5rem;
    border: 1px solid rgba(255,255,255,0.1);
    position: relative;
    overflow: hidden;
}

.hero-section-home::before {
    content: '';
    position: absolute;
    top: -50%;
    right: -30%;
    width: 100%;
    height: 200%;
    background: radial-gradient(circle, rgba(255,255,255,0.1) 0%, transparent 50%);
    pointer-events: none;
}

.hero-section-clearance {
    background: linear-gradient(135deg, var(--primary-color) 0%, var(--secondary-color) 100%);
    color: white;
    padding: 2.5rem 2rem;
    border-radius: 16px;
    margin-bottom: 2rem;
    border: 1px solid rgba(255,255,255,0.1);
    position: relative;
    overflow: hidden;
}

.hero-section-clearance::before {
    content: '';
    position: absolute;
    top: -30%;
    right: -20%;
    width: 80%;
    height: 160%;
    background: radial-gradient(circle, rgba(255,255,255,0.08) 0%, transparent 50%);
    pointer-events: none;
}

.text-white-75 {
    color: rgba(255,255,255,0.9) !important;
}

/* Styling épuré */
.medical-icon {
    color: var(--primary-color);
    font-size: 1.1rem;
}

.section-divider {
    height: 1px;
    background-color: var(--medium-gray);
    margin: 1.5rem 0;
}